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If traveling into St. Louis on I-70 East: Exit on Memorial Drive East. Turn right at the third light (Market Street). Stay on Market Street until 18th Street. The Hyatt will be on your left.
If traveling into St. Louis on I-64/US 40 East: Exit at 20th and Chestnut. Turn right at the light (20th Street). Turn left at the next light (Market Street). The Hyatt will be on your right.
If traveling into St. Louis from Illinois on either I-70 West, I-64 West or I-55 South: All three Interstates will temporarily merge together and cross the Mississippi River on the Poplar Street Bridge. While on the bridge, stay in the left-hand lanes and follow the signs for I-64 West. Once across the bridge you stay on I-64 for approximately one mile. Take the Market and 21st Street Exit. Turn right at the light (Market Street). The Hyatt will be three blocks up on your right.
If traveling into St. Louis on I-55 North: Take the Memorial Drive Exit. Turn left onto Market Street. Stay on Market Street until 18th Street. The Hyatt will be on your left.
If traveling into St. Louis on I-44 East: Take the Jefferson Avenue Exit. Turn left at the light. Turn right onto Market Street. Stay on Market Street until 18th Street. The Hyatt will be on your left.
