Driving the Byway
- The San Juan Skyway starts in Durango, CO, at the intersection of US 160 and US 550.
- Drive north on US 550 and continue as US 550 turns to Main Ave.
- Drive north to Million Dollar Hwy in Silverton, CO.
- Drive northwest on Million Dollar Hwy to Main St. in Quray, CO.
- Continue north to Sherman St, then head west to CO 145, northwest of Placerville, CO.
- Head southeast on CO 145 to Dolores, CO, then drive west to Mancos Rd.
- Continue east to US 550 in Durango, CO, where the byway ends.