Ohio River Scenic Byway

National Scenic BywayIllinois, Indiana, Ohio

Driving the Byway

Driving from west to east, the Ohio River Scenic Byway generally follows the Ohio River across the southern border of three states: Illinois, Indiana, and Ohio.

Illinois Section

The Illinois portion of the Ohio River Scenic Byway generally follows the Ohio River from Missouri/Kentucky to Indiana across the southern part of Illinois.

  • The byway starts at the conjunction of the Ohio and Mississippi Rivers near Fort Defiance State Park. Drive IL-37 north through Cairo, Mounds, and Olmsted, IL.
  • At Grand Chain leave IL-37 and turn east.
  • Travel through Joppa, Metropolis, Brookport and Unionville.
  • At New Liberty turn north and drive through Bay City to Golconda and IL-146.
  • Continue on IL-146, following the Ohio River north and east through Pope and Hardin counties.
  • Near Cave-in Rock State Park in Hardin County, turn north on IL-1.
  • Turn east at the junction with IL-13.
  • At Shawneetown go north to New Haven.
  • Take IL-141 east to the Illinois-Indiana border where the route number changes to IN-62 and the Indiana portion of the Ohio River Scenic Byway begins.

Indiana Section

In Indiana, the byway begins on State Route 62.

  • Starting on the IL-IN border, head east on Route 62.
  • Cross Interstate 164 and take State Route 66 south and east as it meanders across the state, through Tell City and Hoosier National Forest.
  • In Hoosier National Forest Route 66 turns north.
  • At Sulphur in the Hoosier National Forest, take State Route 62 east to Louisville and on north to Madison.
  • At Madison take State Route 56 east.
  • State Route 56 becomes State Route 156 and then turns back into 56.
  • At Aurora, SR 56 becomes Highway 50.
  • Follow this to the state line, where the Indiana part of the byway ends and the Ohio part begins.

Ohio Section

  • The byway begins near Cincinnati, Ohio on Highway 50.
  • In Cincinnati take Highway 52 southeast.
  • Follow Highway 52 as it meanders across the state. Near Proctorville Highway 52 becomes State Route 7.
  • After Pomeroy take State Route 124 southeast towards Minersville.
  • Take State Route 338 south at Racine and follow it until it reunites with SR 124.
  • Follow SR 124 to Little Hocking where it reunites with Highway 7.
  • The road enters Wayne National Forest about 7 miles after Marietta and exits the forest after 27 miles.
  • Follow Highway 7 to the end of the byway, at East Liverpool.