| AC | Advance construction |
| ADA | Americans with Disabilities Act of 1990 |
| ADT | Average daily traffic |
| ATS | Alternative transportation systems |
| AVL | Automatic vehicle location |
| BAC | Blood alcohol concentration |
| BCA | Benefit-cost analysis |
| BCR | Benefit-cost ratio |
| BLM | Bureau of Land Management |
| BOO | Build-Own-Operate |
| BOT | Build-Operate-Transfer |
| BPR | U.S. Bureau of Public Roads (predecessor of U.S. Federal Highway Administration) |
| BRT | Bus rapid transit |
| CEV | Capacity-equivalent vehicle |
| CFR | Code of Federal Regulations |
| CFS | Commodity Flow Survey |
| CIP | Capital improvement program |
| Combo | Combination truck |
| CPI | Consumer Price Index |
| CTAA | Community Transportation Association of America |
| DBFO | Design-Build-Finance-Operate |
| DBOM | Design-Build-Operate-Maintain |
| DMS | Dynamic message sign |
| DoD | U.S. Department of Defense |
| DOI | U.S. Department of Interior |
| DOT | U.S. Department of Transportation |
| DVMT | Daily vehicle miles traveled |
| FAF | Freight Analysis Framework |
| FARS | Fatality Analysis Reporting System |
| FHWA | U.S. Federal Highway Administration |
| FTA | U.S. Federal Transit Administration |
| FY | Fiscal year |
| GAN | Grant Anticipation Note |
| GARVEE | Grant Anticipation Revenue Vehicle |
| GDP | Gross domestic product |
| HCM | Highway Capacity Manual |
| HERS | Highway Economic Requirements System |
| HERS-ST | Highway Economic Requirements System, State Version |
| HFCS | High Functional Classification System |
| HOFM | Office of Freight Management and Operations |
| HOT | High occupancy toll |
| HOV | High occupancy vehicle |
| HPMS | Highway Performance Monitoring System |
| HPMS-AP | HPMS Analytical Process |
| HSM | Highway Safety Manual |
| HTF | Highway Trust Fund |
| IDAS | ITS Deployment Analysis System |
| IHSDM | Interactive Highway Safety Design Model |
| ILEV | Inherently low-emission vehicle |
| IP | Internet protocol |
| IRI | International Roughness Index |
| ISTEA | Intermodal Surface Transportation Efficiency Act of 1991 |
| ITIP | Intelligent transportation infrastructure program |
| ITS | Intelligent transportation systems |
| LNG | Liquefied natural gas |
| LPG | Liquefied petroleum gas |
| MPO | Metropolitan planning organization |
| MR&R | Maintenance, repair, and rehabilitation |
| MTA | Mass Transit Account |
| NBI | National Bridge Inventory |
| NBIAS | National Bridge Investment Analysis System |
| NBIS | National Bridge Inspection Standards |
| NCHRP | National Cooperative Highway Research Program |
| NHS | National Highway System |
| NHTS | National Household Travel Survey |
| NHTSA | National Highway Traffic Safety Administration |
| NPS | National Park Service |
| NPTS | Nationwide Personal Transportation Survey |
| NTD | National Transit Database |
| NYCT | New York City Transit |
| OST | Office of the Secretary of Transportation |
| PMT | Passenger miles traveled |
| PPP | Public-private partnership |
| PSR | Present Serviceability Rating |
| PV | Passenger vehicle |
| Q&A | Question and answer |
| SAFETEA-LU | Safe, Accountable, Flexible, Efficient Transportation Equity Act: A Legacy for Users |
| SDDCTEA | Surface Deployment and Distribution Command Transportation Engineering Agency |
| SDELP | San Diego Expressway Limited Partnership |
| SEP-15 | Special Experimental Project No. 15 |
| SIB | State Infrastructure Bank |
| SQC | Synthesis, Quantity, and Condition |
| STRAHNET | Strategic Highway Network |
| SU | Single-unit truck |
| SUV | Sport utility vehicle |
| TDM | Travel demand management |
| TEA-21 | Transportation Equity Act for the 21st Century |
| TERM | Transit Economic Requirements Model |
| TIFIA | Transportation Infrastructure Finance and Innovation Act |
| TIM SA | Traffic Incident Management Self-Assessment |
| TMA | Transportation Management Area |
| TMC | Transportation management center |
| TPMS | Transit Performance Monitoring System |
| TTC-35 | Trans Texas Corridor |
| TTI | Texas Transportation Institute |
| USC | United States Code |
| USFS | U.S. Forest Service |
| USFWS | U.S. Fish and Wildlife Service |
| VIUS | Vehicle Inventory and Use Survey |
| V/SF | Volume to service flow |
| VMS | Variable message signs |
| VMT | Vehicle miles traveled |
| VRM | Vehicle revenue miles |
| WZSA | Work Zone Self-Assessment |
